On 4 different systems I was only able to include in guicast/Makefile, the CFLAGS += $(-fsanitize=alignment) and set the LDFLAGS environment variable to -fsanitize=alignment in order to compile. But when I ran bin/cin I never got any errors of the type "bctheme.C:458:15: runtime error: load of misaligned address". This was Fedora 32, Ubuntu 16, Debian 32-bit 9.1, and Debian 11.0. I only loaded a file, played a little of it, and added a plugin as a test (maybe there was something in particular I should have tried?)